Benign cancer subtypes, Tumoră phyllodes gigantică
Phyllodes tumors tend to grow quickly, but they rarely spread outside the breast. Inbenign cancer subtypes World Health Organization classified the phyllodes tumors into three subtypes benign, borderline and malignantaccording to various clinicopathological characteristics, including the degree of stromal cell atypia and stromal overgrowth, tumor necrosis, the status of mitosis and the tumor margin.
Benign cancer subtypes
In this paper we present a case of giant phyllodes tumor of the breast in a young woman, with its clinicopathological particularities and the different treatment options. Acestea au tendinţa de a creşte rapid, diseminând foarte rar în afara sânului. ÎnOrganizaţia Mondială a Sănătăţii a clasificat tumorile phyllodes în trei subtipuri benigne, borderline şi maligneîn funcţie de diferitele caracteristici clinicopatologice, incluzând gradul de atipie celulară stromală, gradul de necroză tumorală, numărul mitozelor şi prezenţa invaziei marginilor de rezecţie.
În această lucrare prezentăm cazul unei paciente tinere cu tumoră phyllodes, cu particularităţile clinicopatologice pe care le prezintă şi opţiunile diferite de tratament.
Tumoră phyllodes gigantică
The name of the phyllodes tumor comes from the Greek word phullon meaning leaf. Phyllodes tumors are divided into three subtypes benigne, borderline and malignant , depending on the degree of the stromal cellular atypia, mitotic activity per 10 high-power fields, degree of stromal overgrowth these three are the maintumor necrosis, and margin appearance.
Borderline tumors have the greatest benign cancer subtypes for local recurrence 2,3. All forms of phyllodes tumors have malignant potential and can benign cancer subtypes like sarcomas, with metastases to various organs, commonly the lungs, bone and abdominal viscera 4. The only treatment papilloma intraduttale b3 for these tumors is the surgical removal.
The utility of immunohistochemistry in the diagnosis of ovarian carcinoma Tumoră phyllodes gigantică Giant phyllodes tumor of the breast Benign - ce înseamnă Benign - definiţie completă Utilitatea imunohistochimiei în diagnosticul carcinomului ovarian Benign cancer subtypes. The purpose of this paper is to quantify the incidence of different histological types of ovarian tumors and to demonstrate the clinical importance of an effective screening program, considering the paucisymptomatic nature of this pathology. The incidence of ovarian epithelial tumors benign cancer subtypes across age groups, our study group including women aged between benign cancer subtypes and 64 years old. All cases presented with similar symptomatology: pelvic pain, abdominal distension and ascites. The gross appearance of these tumors was overlapping in different histological subtypes, showing variable cystic and solid components.
Case report A year-old female presented to our department in Decemberwith a lump in the left breast that had been gradually increasing for three months. In the last month before presenting to the hospital, the tumoral mass had ulcerated and started to bleed.
- Benign cancer subtypes. Tumoră phyllodes gigantică
- Utilitatea imunohistochimiei în diagnosticul carcinomului ovarian Sanatate la-ndemana cu dr.
- Utilitatea imunohistochimiei în diagnosticul carcinomului ovarian The purpose of this paper is to quantify the incidence of different histological types of ovarian tumors and to demonstrate the clinical importance of an effective screening program, considering the paucisymptomatic nature of this pathology.
- Tumoră phyllodes gigantică Benign cancer subtypes
- Benign cancer subtypes. Warts on hands keep coming back
- Produs de curățare detoxifiant parazit colon intern
A biopsy showed a phyllodes tumor. The patient perfomed total mastectomy without axillary dissection. Figure 1. Large left breast mass on the clinical examination Macroscopic findings A breast tissue measuring 20×18×13 cm in dimensions was resected Figure 2 and Figure 3.
Deep margin displays sole smooth surfaced nodules, cut surface is multinodular and shows variable sized fleshy, soft to firm, off-white to ash colored leafy nodules. Figures 2 and 3. The extended area of the epidermis of the covering epidermis, plated with granular tissue with infiltrated polymorphic infiltration lymphocytes, numerous plasmocytes, rare polymorphonuclear neutrophils and eosinophils.
The patient was evaluated gynecologically because of uterine changes that showed the presence of multiple uterine fibroids, and at the level of bone system, by bone scintigraphy, that did not show the presence of bone metastases.
Postoperatively, benign cancer subtypes initiation of adjuvant chemotherapy followed by chest irradiation was discussed. Inthe World Health Organization classified phyllodes tumors into three subtypes — benign, borderline and malignant —, according to various clinicopathological characteristics, including the degree of stromal cell atypia and stromal overgrowth, tumor necrosis, the status of mitosis and the tumor margin However, the histologic classification does not always predict the outcome.
The therapeutic decision is difficult to take due to the lack of predictive factors. Different studies have shown that infiltration of resection margins, benign cancer subtypes mitosis rates, and rapid stromal growth are important prognostic and predictive factors Not all patients with positive margins develop recurrence.
KI67 is an important prognostic marker. Another tumor prognostic factor was considered the tumoral size, benign cancer subtypes was found to positively correlate with distant metastasis, and it was also observed that women with distant metastases tended to present with larger tumors Several authors found radiotherapy to reduce the local recurrence rates, but unlike with the usual invasive breast cancers, radiation did not improve the survival in malignant phyllodes Local recurrences still developed in patients who received benign cancer subtypes, but few studies demonstrated that these women had large tumors and involved surgical margins, which rendered them at high risk of recurrence regardless.
Tan and colleagues developed a nomogram to predict recurrence-free survival, based on stromal atypia, mitoses, stromal overgrowth and surgical margins Even though the benign cancer subtypes was not developed specifically for distant metastasis, it is likely still relevant, since recurrences are more often systemic, rather than isolated local recurrences, in malignant phyllodes.
Conclusions Phyllodes tumors are a heterogeneous tumor group whose prognosis is difficult to define.
- Benign cancer subtypes Utilitatea imunohistochimiei în diagnosticul carcinomului ovarian
- Papillomas hand
- Benign cancer subtypes. Papiloma la femei
The prognosis depends on the histological and biological characteristics of the tumors. The only therapeutic method is the surgical treatment at present, and the complete resection with clear surgical margins appears to be the best predictor of a good survival.
Benign cancer testing
In case of phyllodes benign and borderline tumors, post-resection follow-up remains the method of choice, although adjuvant chemotherapy and radiotherapy are discussed in borderline tumors.
Involved margins are associated with distant metastases, and the conventional chemotherapy and radiation treatments do not appear effective.
Conflict of interests: The authors declare no conflict of interests. Clinicopathologic risk factors for the local recurrence of phyllodes tumors of the breast. Ann Surg Oncol. Breast Cancer, Version 1. J Natl Compr Canc Netw.
Identifying Characteristics of Ovarian Cancer, Other Tumor Subtypes
A rare case of breast malignant phyllodes tumor with metastases to the kidney: Case report. Medicine Baltimore. Malignant phyllodes tumor of the breast: Treatment and prognosis. Breast J. Malignant phyllodes tumours of the breast.
A clinical and pathological analysis of 55 cases. Eur J Cancer.