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Perioperative management of a patient with Krukenberg tumor - a case report High-grade ovarian peritoneal cancer bloating carcinoma in a young woman - case report and literature review Managementul perioperator al unui pacient cu tumoră Krukenberg - studiu de caz Peritoneal cancer with ascites.

Ovarian peritoneal tratament de rezonanță a paraziților with ascites serous carcinoma is a type of malignancy that is rare among young adult women, being more frequent in postmenopausal wo­men. We present the case of a young woman with this type of malignant tumor, who in addition already had extension beyond the pelvis at the time of diagnosis, peritoneal cancer with ascites is a poor prognostic factor.

Case report.

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We repot the case of a year-old woman who was admitted in our hospital with pelvic pain and ascites and also with suspicion of peritoneal carcinomatosis. After complex surgery, the histopathological result was bilateral ova­rian high-grade serous carcinoma with invasion of the perivesical peritoneum, mesoappendix, multiple omental involvement and one regional lymph node me­tastasis.

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Afterwards, she was submitted for oncologic treatment. The follow-up, three years later, revealed patient survival, but with peritoneal carcinomatosis status on abdominal-pelvic CT scan. Our work brings together reports of young women worldwide facing peritoneal cancer with ascites form of cancer and underlines the fact that, regardless of age, reproductive women are at risk of developing an aggressive and deadly disease, and that clinical, biological and imaging screening should be increased from an early age.

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Keywords high-grade serous carcinoma, young women, screening Rezumat Obiectiv. Carcinomul ovarian seros cu grad înalt de malignitate este un tip de cancer rar întâlnit la femeile tinere, fiind mai frecvent la femeile în postmenopauză. Vă peritoneal cancer bloating cazul unei femei tinere cu această formă de tumoră malignă, care se afla deja într-un stadiu avansat cu extensie extrapelviană la momentul diagnosticului, ceea ce reprezintă un factor de prognostic negativ.

Prezentare de caz. Raportăm cazul peritoneal cancer bloating femei de 36 de ani care s-a prezentat la spitalul nostru cu dureri pelviene și ascită, suspicionându-se carcinomatoză peritoneală.

Peritoneal cancer with ascites.

După intervenția chirurgicală histerectomie totală cu anexectomie bilaterală, apendicetomie și evidare ganglionară peritoneal cancer with ascitesrezultatul histopatologic a fost: carcinom ovarian seros de grad înalt, bilateral, cu invazia peritoneului perivezical, mezoapendice, omentală, precum și a unui limfoganglion regional.

Pacienta a supraviețuit și s-a prezentat periodic la control, însă la trei ani de la operație, la examenul CT abdomino-pelvian, s-au identificat semne de carcinomatoză peritoneală. Lucrarea noastră aduce în prim plan raportări de cazuri ale unor paciente tinere din întreaga lume suferind de această formă de cancer și subliniază faptul că, indiferent de vârstă, femeile aflate în perioada reproductivă sunt la risc de a dezvolta o afecțiune ovariană agresivă și letală, de aceea este important ca screeningul peritoneal cancer with ascites, biologic și imagistic să fie început de la o vârstă timpurie.

Serous carcinoma is most often diagnosed peritoneal cancer bloating the sixth and seventh decade, with a mean age of high-grade tumors of 63 years old 3. Diagnosis is often delayed because symptoms are non-specific and include: abdominal pain, peritoneal cancer with ascites, gastrointestinal symptoms nausea, anorexia, constipationhigh urinary frequency, vaginal bleeding 1,3. The treatment is represented by surgery and chemotherapy, and although most of them initially respond to chemotherapy, the response is not durable, compared with low-grade serous carcinomas, which are less likely to respond to chemotherapy, but have a more favorable prognosis, based on peritoneal cancer bloating indolent growth 4.

Case report We report the case of a year-old woman with previous complains of abdominal pain and moderate abdominal distension who was admitted in our hospital. Following ultrasound examination Figure 1we detected a large left ovarian tumor multiple septa with intense vascularity during Doppler inspection and ascites.

peritoneal cancer bloating

Managementul perioperator al unui pacient cu tumoră Krukenberg - studiu de caz After CT examination of the abdomen and pelvis, peritoneal carcinomatosis was suspected. CA and HE4 markers were slightly elevated. Figure 1. Figure 2. Macroscopic appearance of the left ovary; note the presence of peritoneal cancer with ascites solid and cystic areas with yellow-brown fluid On macroscopy, both ovaries were enlarged, the left one measuring 90 mm in diameter and the other 5 cm.

Cancerul trompelor uterine - cauze și metode de tratament - Cancer Cancerul trompelor uterine Peritoneal cancer bloating Peritoneal cancer bloating anual trecea toate analizele medicale pentru a verifica dacă maladia nu a recidivat, diagnosticul de cancer abdominal l-a aflat destul de târziu.

On cut section the peritoneal cancer bloating ovary presented multiple peritoneal cancer bloating and cystic areas with yellow-brown fluid Figure 2 ; similar appearance was also detected in the lateral margin of the right ovary. Figure 3. Solid area with severe pleomorphism and numerous mitosis H.

Cystic area with papillary and micropapillary structures H. Estrogen receptor positivity - IHC x40 The histopathological examination concluded bilateral ovarian high-grade serous carcinoma with invasion of the perivesical peritoneum, mesoappendix, multiple omental involvement and one regional lymph node metastasis stage IIICwith no evidence of metastasis to extraabdominal organs or parenchymal metastasis. It is important to distinguish between primary ovarian cancer and metastatic tumors in the ovary because their management is different, in terms of treatment and follow-up.

We report the perioperative management of a year-old female patient with bilateral Krukenberg tumors. Este important să se facă distincţia între cancerul ovarian primar şi peritoneal cancer with ascites metastatice ale ovarului, deoarece managementul lor este diferit în peritoneal cancer bloating ce priveşte tratamentul şi urmărirea. Raportăm managementul perioperator al unei paciente de 40 peritoneal cancer bloating ani, cu tumori bilaterale Krukenberg.

peritoneal cancer bloating

The patient was submitted for further oncologic treatment. Figure 6. In a published study, A.

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The two-tier system of classification of serous carcinoma is composed of peritoneal cancer bloating and high-grade tumors. The criteria for sub-classifying to one or the other are histological, represented by nuclear atypia and mitotic activity 3,6.

According to age incidence, the low-grade tumors occur at younger age, with statistically declared one decade earlier than high-grade counterpart 1,6. More than their histological differences, the two serous­ malignant entities have been described in literature peritoneal cancer bloating come peritoneal cancer with ascites different development pathways.

Type I carcinoma low-grade progresses from borderline or benign tumors and are thought to retain their low-grade appearance even after disease recurrence, and peritoneal cancer bloating II carcinoma high-grade were described mostly as de novo tumors, although a small percent appear to have evolved from a low-grade tumor 6,7.